This isn't so useful anymore since Jeremy redid the "print friendly" pages on geocaching.com, but it's included for completeness.
The Cache Simplifier is a bit of VBScript code and a few registry entries that add a button to your IE toolbar to let you turn this

into this
To install, unzip the file in your Windows directory, then double-click the .reg file and install the registry changes. This should just add the button to your toolbar automatically, but if it doesn't you can add it by hand by right-clicking the toolbar and choosing "Customize..."
The Cache Simplifier will also be added to your Tools menu automatically